Cardiovascular & clot risk

CHA₂DS₂-VASc

Stroke risk factors in atrial fibrillation, with sex category as a risk modifier.

Intended population: Adults with atrial fibrillation or atrial flutter. Treatment requires clinical and bleeding-risk assessment.

Female sex alone is not an indication for anticoagulation. Absolute annual stroke rates vary by cohort and are not estimated here.
Do not use this score alone for mechanical heart valves or rheumatic moderate/severe mitral stenosis; those require a separate anticoagulation pathway.
Review bleeding risks, contraindications, renal function, interactions, and patient preferences; this calculator does not select or dose medication.

Adult with atrial fibrillation or atrial flutter

Age (years)

Sex category used in the original score

Heart failure or left-ventricular dysfunction

History of hypertension

Diabetes

Previous stroke, TIA, or systemic thromboembolism

Vascular disease: prior MI, peripheral arterial disease, or aortic plaque

Sources and scoring references

2023 ACC/AHA/ACCP/HRS atrial fibrillation guideline ↗

Implementation references reviewed October 28, 2026. Verify applicability and unusual or treatment-changing results against the linked references and local guidance.