Kidney function

eGFR (CKD-EPI 2021, race-free)

Adult creatinine-based, race-free estimated glomerular filtration rate.

Intended population: Nonpregnant adults aged 18 or older who are not receiving dialysis, using standardized IDMS-traceable serum creatinine at steady state.

This is an indexed estimate, not measured GFR or a diagnosis of CKD. Creatinine–cystatin C estimates are preferred when greater accuracy is needed, particularly near a clinical decision threshold. Abnormal muscle mass and other non-GFR determinants affect accuracy.
Not for pregnancy or patients receiving dialysis. Pregnancy changes renal physiology, and dialysis alters creatinine independently of native kidney clearance; use an appropriate renal assessment.

Age (years)

Sex coefficient specified by the equation

Serum creatinine (mg/dL)

Creatinine is at a steady state

Patient is not pregnant and is not receiving dialysis

Sources and scoring references

NIDDK: adult race-free eGFR equations and limitations ↗NIDDK: clinical measurements and eGFR accuracy ↗Clinical practice guideline on pregnancy and renal disease (2019), recommendation 4.1.1 ↗

Implementation references reviewed October 28, 2026. Verify applicability and unusual or treatment-changing results against the linked references and local guidance.