Kidney function

Creatinine clearance (Cockcroft–Gault)

Historical adult estimate of creatinine clearance using an explicitly selected weight.

Intended population: Nonpregnant adults not receiving dialysis, with steady-state serum creatinine; original derivation ages 18–92 years.

Actual, ideal or adjusted weight must be selected according to the relevant protocol; the tool does not choose. Not indexed to 1.73 m², not interchangeable with eGFR, and not a medication-dose recommendation. Extreme body composition and ages outside the original cohort reduce confidence.
Not for pregnancy or patients receiving dialysis. Pregnancy changes renal physiology, and dialysis alters creatinine independently of native kidney clearance; use an appropriate renal assessment.

Age (years)

Sex coefficient specified by the equation

Weight selected for this equation (kg)

Serum creatinine (mg/dL)

Creatinine is at a steady state

Patient is not pregnant and is not receiving dialysis

Sources and scoring references

Cockcroft and Gault: Prediction of creatinine clearance (1976) ↗NIDDK: clinical measurements and eGFR accuracy ↗Clinical practice guideline on pregnancy and renal disease (2019), recommendation 4.1.1 ↗

Implementation references reviewed October 28, 2026. Verify applicability and unusual or treatment-changing results against the linked references and local guidance.