Electrolytes and acid–base

Sodium correction for hyperglycemia

Estimate glucose-adjusted sodium with an explicitly selected published coefficient.

Intended population: Hyperglycemia at or above 100 mg/dL; a physiologic estimate rather than a treatment target.

The relationship is nonlinear, especially above glucose 400 mg/dL; neither fixed coefficient is exact. Assess tonicity, volume status and serial laboratory values; this result does not prescribe sodium correction or fluids.

Measured sodium (mmol/L)

Serum glucose (mg/dL)

Correction coefficient per 100 mg/dL above 100

Sources and scoring references

Hillier et al.: hyperglycemic sodium correction (1999) ↗European clinical practice guideline on hyponatraemia (2014) ↗

Implementation references reviewed October 28, 2026. Verify applicability and unusual or treatment-changing results against the linked references and local guidance.